Many varieties of seedless grapes are now available, but if you have grapes with seeds, here are two ways to remove them quickly and easily. To deseed with a paper clip: open a paper clip, insert the narrow end at the stalk end of the grape and twist to poke out the seeds.How-to-Deseed-GrapesTo deseed with a knife: halve the grapes, then flick out the seeds with the tip of a small knife.